Basu J
Medical College, Calcutta.
J Indian Med Assoc. 1991 Jan;89(1):16.
The neuroleptic malignant syndrome is an exceedingly rare but potentially fatal condition characterized by parkinsonian type rigidity, rise of temperature and altered consciousness. This idiosyncratic side-effect of almost all psychotic drugs though rare may occur even when neuroleptics are used for a short period. Here a very rare presentation of a case, of neuroleptic malignant syndrome appearing 2 days following 2nd dose of injection fluphenazine decanoate (0.5 ml) IM in whom 1st dose having 30 days prior to the 2nd one did not show any adverse effect, is being reported.
抗精神病药恶性综合征是一种极为罕见但可能致命的疾病，其特征为帕金森氏症样僵硬、体温升高和意识改变。几乎所有精神药物的这种特异质性副作用虽然罕见，但即使在短期内使用抗精神病药时也可能发生。本文报告了一例非常罕见的病例，患者在第二次注射癸酸氟奋乃静（0.5毫升，肌肉注射）后两天出现抗精神病药恶性综合征，第一次注射在第二次注射前30天，未出现任何不良反应。
