The Dermatology Centre, 124-42 Avenue South West, Calgary, Alberta T2S3B3, Canada.
Dermatol Clin. 2010 Jul;28(3):525-34. doi: 10.1016/j.det.2010.03.015.
Metronidazole is a synthetic nitroimidazole derivative with antimicrobial and antiinflammatory properties. It was the first topical therapy approved solely for rosacea and remains a cornerstone of rosacea management. This article reviews the optimal use of topical metronidazole in the treatment of rosacea and other innovative but off-label dermatologic uses reported in the literature.
甲硝唑是一种合成的硝基咪唑衍生物，具有抗菌和抗炎特性。它是第一种专门批准用于酒渣鼻的局部治疗药物，仍然是酒渣鼻治疗的基石。本文回顾了局部甲硝唑在治疗酒渣鼻和文献中报道的其他创新但超适应证皮肤科用途的最佳使用方法。
