Instituto de Tecnología Química (UPV-CSIC), Universidad Politécnica de Valencia, Consejo Superior de Investigaciones Científicas, Avenida de los Naranjos s/n. 46022, Valencia, Spain.
Chem Commun (Camb). 2010 Jul 21;46(27):4965-7. doi: 10.1039/c0cc00176g. Epub 2010 May 28.
Two cholic acid (ChA) analogues, containing a 4-nitrobenzo-2-oxa-1,3-diazole (NBD) moiety at C-3, were incorporated into ChA aggregates and submitted to fluorescence quenching by the two enantiomers of several tryptophan derivatives. In all cases, a significant stereodifferentiation was observed; the most remarkable effect was found when comparing the 3alpha and the 3beta diastereomers.
两种胆酸（ChA）类似物，在 C-3 位上含有 4-硝基苯并-2-氧代-1,3-二氮唑（NBD）部分，被掺入 ChA 聚集体中，并通过几种色氨酸衍生物的两种对映体进行荧光猝灭。在所有情况下，都观察到显著的立体差异；当比较 3α和 3β非对映异构体时，发现了最显著的效果。
