The Washington Cancer Institute, Washington Hospital Center, Washington, District of Columbia 20010, USA.
J Surg Oncol. 2010 Jun 15;101(8):713-24. doi: 10.1002/jso.21484.
In the past, cancer surgery for gastrointestinal malignancy focused on clearance (an R-0 resection) and containment (no surgically induced spillage of cancer cells). A new responsibility that cancer surgeons must accept is the knowledgeable prevention or treatment of cancer that disseminates to peritoneal surfaces. Carcinomatosis can be prevented and can be successfully treated using cytoreductive surgery and perioperative chemotherapy.
过去,胃肠道恶性肿瘤的外科手术主要侧重于清除(R0 切除)和隔离(无癌细胞手术性播散)。肿瘤外科医生必须承担新的责任,即了解并预防可能播散到腹膜表面的癌症,或者对其进行治疗。采用细胞减灭术和围手术期化疗可以预防肿瘤播散并成功治疗肿瘤转移。