Takahama Makoto, Yamamoto Ryoji, Nakajima Ryu, Tsukioka Takuma, Tada Hirohito
Department of General Thoracic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima Hondori, Miyakojima-ku, Osaka 534-0021, Japan.
Interact Cardiovasc Thorac Surg. 2010 Aug;11(2):150-3. doi: 10.1510/icvts.2009.230003. Epub 2010 May 31.
The purpose of this study was to investigate the clinical characteristics of chronic hemodialysis (HD) patients with lung cancer who underwent pulmonary resection at the authors' hospital. Subjects were 24 chronic HD patients (1.1%) from among 2178 patients who underwent pulmonary resection for lung cancer at our hospital between December 1994 and March 2009. Subjects included 20 males (83.3%), and mean age was 65.9 years. Twenty-two patients underwent lobectomy, one underwent a wedge resection and one underwent a segmentectomy. Histological diagnoses included squamous cell carcinoma in 12 patients, adenocarcinoma in nine, small cell carcinoma in two and adenosquamous carcinoma in one. The distribution of pathological staging was IA in nine cases, IB in five, IIB in five, IIIA in three, and IIIB in two. There was no operative mortality, and the overall morbidity rate was 58.3%. Disease-free interval was six to 102 months with a median of 54 months, and the five-year survival rate was 43.0%. Cases of pulmonary resection for lung cancer in chronic HD patients were investigated. There were no operative deaths or deaths in hospital, but three patients had serious complications. These data indicate that surgery can be performed safely with appropriate HD and general management in the perioperative period.
本研究的目的是调查在作者所在医院接受肺切除术的慢性血液透析（HD）肺癌患者的临床特征。研究对象为1994年12月至2009年3月期间在我院因肺癌接受肺切除术的2178例患者中的24例慢性HD患者（1.1%）。研究对象包括20名男性（83.3%），平均年龄为65.9岁。22例患者接受了肺叶切除术，1例接受了楔形切除术，1例接受了肺段切除术。组织学诊断包括12例鳞状细胞癌、9例腺癌、2例小细胞癌和1例腺鳞癌。病理分期分布为IA期9例、IB期5例、IIB期5例、IIIA期3例、IIIB期2例。无手术死亡，总发病率为58.3%。无病生存期为6至102个月，中位数为54个月，五年生存率为43.0%。对慢性HD患者肺癌肺切除术病例进行了调查。无手术死亡或住院死亡，但3例患者出现严重并发症。这些数据表明，在围手术期进行适当的血液透析和综合管理，手术可以安全进行。
