Minoda Y, Ikebuchi M, Kobayashi A, Iwaki H, Inori F, Nakamura H
Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka 545-8585, Japan.
J Bone Joint Surg Br. 2010 Jun;92(6):794-8. doi: 10.1302/0301-620X.92B6.23159.
Bone mineral density (BMD) around the femoral component has been reported to decrease after total knee replacement (TKR) because of stress shielding. Our aim was to determine whether a cemented mobile-bearing component reduced the post-operative loss of BMD. In our study 28 knees receiving a cemented fixed-bearing TKR were matched with 28 receiving a cemented mobile-bearing TKR. They underwent dual-energy x-ray absorptiometry, pre-operatively and at three weeks and at three, six, 12, 18 and 24 months post-operatively. The patients were not taking medication to improve the BMD. The pre-operative differences in the BMD of the femoral neck, wrist, lumbar spine and knee in the two groups were not significant. The BMD of the femur decreased postoperatively in the fixed-bearing group, but not the mobile-bearing group. The difference in the post-operative change in the BMD in the two groups was statistically significant (p < 0.05) at 18 and 24 months. Our findings show that a cemented mobile-bearing TKR has a favourable effect on the BMD of the distal femur after TKR in the short term. Further study is required to determine the long-term effects.
据报道,由于应力遮挡,全膝关节置换术(TKR)后股骨假体周围的骨矿物质密度(BMD)会降低。我们的目的是确定骨水泥固定的活动平台假体是否能减少术后骨密度的损失。在我们的研究中,28例接受骨水泥固定平台TKR的膝关节与28例接受骨水泥活动平台TKR的膝关节进行匹配。他们在术前、术后三周以及术后三、六、十二、十八和二十四个月接受双能X线吸收测定。患者未服用改善骨密度的药物。两组患者术前股骨颈、腕部、腰椎和膝关节的骨密度差异无统计学意义。固定平台组术后股骨骨密度降低,而活动平台组未降低。两组术后骨密度变化的差异在18个月和24个月时具有统计学意义(p<0.05)。我们的研究结果表明,骨水泥固定的活动平台TKR在短期内对TKR术后股骨远端的骨密度有有利影响。需要进一步研究以确定其长期影响。