Miedinger David, Linz Anette, Praehauser Claudia, Chhajed Prashant N, Buess Christian, Schafroth Török Salome, Bucher Heiner C, Tamm Michael, Leuppi Jörg D
Pulmonary Medicine, Department of Internal Medicine, University Hospital, Basel, Switzerland.
Prim Care Respir J. 2010 Jun;19(2):163-9. doi: 10.4104/pcrj.2010.00030.
To evaluate the prevalence and predictors of airflow limitation among smokers aged > or =40 years visiting primary care practices in Switzerland, and the correlation between airflow limitation and patient-reported symptoms.
General practitioners (GPs) were invited to participate in the study via letter. Airflow limitation was measured using an EasyOne spirometer without administration of a bronchodilator, and patient-reported symptoms were evaluated using an interviewer-administered questionnaire.
15,084 subjects recruited by 440 GPs had acceptable quality spirometry traces; 8,031 of these (53%) had symptom data available and were included in this analysis. Only 18.5% of the GP consultations were for respiratory reasons. In total, 29% of individuals had pre-bronchodilator airflow limitation suggesting chronic obstructive pulmonary disease according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD)/Hardie interpretation. The interviewer-administered questionnaire indicated that 58% of individuals had at least one current symptom - cough, sputum production, or dyspnoea. There were no differences in lung function for patients answering yes or no to symptom questions.
Pre-bronchodilator airflow limitation and patient-reported respiratory symptoms are frequent among smokers, but short dichotomous questions about symptoms are not useful for identifying patients with airflow limitation. Spirometry can identify patients with early airflow limitation in general practice. However, poor quality of spirometry, even with an automated feedback and quality control spirometer, remains an issue.
评估年龄≥40岁且前往瑞士初级医疗诊所就诊的吸烟者气流受限的患病率及预测因素,以及气流受限与患者报告症状之间的相关性。
通过信件邀请全科医生(GPs)参与研究。使用EasyOne肺量计在未使用支气管扩张剂的情况下测量气流受限情况,并使用访员管理的问卷评估患者报告的症状。
440名全科医生招募的15084名受试者有可接受质量的肺量计记录;其中8031名(53%)有症状数据并纳入本分析。全科医生会诊中仅18.5%是出于呼吸相关原因。根据慢性阻塞性肺疾病全球倡议(GOLD)/哈迪解读标准,总计29%的个体存在支气管扩张剂使用前气流受限,提示慢性阻塞性肺疾病。访员管理的问卷显示,58%的个体至少有一项当前症状——咳嗽、咳痰或呼吸困难。对症状问题回答“是”或“否”的患者在肺功能方面无差异。
支气管扩张剂使用前气流受限和患者报告的呼吸道症状在吸烟者中很常见,但关于症状的简短二分法问题对识别气流受限患者无用。肺量计检查可在全科医疗中识别早期气流受限患者。然而,即使使用自动反馈和质量控制的肺量计,肺量计检查质量差仍是一个问题。