Zarghooni K, Röllinghoff M, Siewe J, Fätkenheuer G, Seifert H, Eysel P, Sobottke R
Klinik und Poliklinik für Orthopädie und Unfallchirurgie der Universität zu Köln.
Dtsch Med Wochenschr. 2010 Jun;135(23):1182-5. doi: 10.1055/s-0030-1255128. Epub 2010 May 31.
A 21-year-old man presented with severe lumbar back pain and progressive paraparesis with clinical signs of spondylitis. Laboratory findings revealed elevated infectious parameters. Because of a positive Mantoux-Test he had been treated with quadruple tuberculostatic drugs for eight weeks without prior identification of the causative pathogen.
Magnetic resonance imaging of the spine revealed a multisegmental spondylitis of the lumbar vertebrae (L3 - L5) with epidural empyema. Computed tomography (CT) of the abdomen confirmed large bilateral abscesses in the psoas muscles.
The findings supported the diagnosis of spondylitis. The antibiotic regimen was continued. CT-guided drainage was placed in both psoas muscles. Laminectoma of L3 - 5 and dorsal spondylodesis of L2 - S1 were performed immediately. Mycobacterium tuberculosis was cultured from the intraoperative biopsies and treated according to the drug sensitivity test. After further surgical debridment and corporectomy of L4 and L5 the infection was successfully treated. Ten weeks after admission the patient was transferred to a neurologic rehabilitation unit for mobilization.
Spondylodiscitis treatment is complex and requires a multidisciplinary approach.
一名21岁男性因严重腰背痛及进行性双下肢轻瘫就诊,伴有脊柱炎临床体征。实验室检查发现感染指标升高。由于结核菌素试验呈阳性,他在未事先确定病原体的情况下接受了四联抗结核药物治疗八周。
脊柱磁共振成像显示腰椎(L3 - L5)多节段脊柱炎伴硬膜外积脓。腹部计算机断层扫描(CT)证实双侧腰大肌有巨大脓肿。
这些检查结果支持脊柱炎的诊断。继续使用抗生素治疗方案。在双侧腰大肌进行了CT引导下引流。立即进行了L3 - 5椎板切除术和L2 - S1后路脊柱融合术。术中活检培养出结核分枝杆菌,并根据药敏试验进行治疗。在进一步进行手术清创以及L4和L5椎体切除术之后,感染得到成功治疗。入院十周后,患者被转至神经康复科进行活动康复。
脊椎椎间盘炎的治疗复杂,需要多学科方法。