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Peptides derived from the third cytoplasmic loop of type 6 serotonin receptor as regulators of serotonin-sensitive adenylyl cyclase signaling system.

作者信息

Shpakov A O, Tarasenko I I, Shpakova E A

机构信息

Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, pr. Morisa Toreza 44, St. Petersburg 194223, Russia.

出版信息

Dokl Biochem Biophys. 2010 Mar-Apr;431:94-7. doi: 10.1134/s1607672910020110.

DOI:10.1134/s1607672910020110
PMID:20514872
Abstract
摘要

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Ross Fiziol Zh Im I M Sechenova. 2006 May;92(5):521-35.
3
[Use of the peptide strategy to study mechanisms of transferring the hormone signal to the cell].
Zh Evol Biokhim Fiziol. 2005 Sep-Oct;41(5):389-403.
4
Sensitivity of adenylyl cyclase signaling system of the mollusk Anodonta cygnea ganglions to serotonin and adrenergic agonists.
Ann N Y Acad Sci. 2005 Apr;1040:466-8. doi: 10.1196/annals.1327.092.
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Molecular analysis of the interaction between the intracellular loops of the human serotonin receptor type 6 (5-HT6) and the alpha subunit of GS protein.人6型血清素受体（5-HT6）细胞内环与GS蛋白α亚基之间相互作用的分子分析
Biochem Biophys Res Commun. 2005 Apr 8;329(2):684-92. doi: 10.1016/j.bbrc.2005.02.040.
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5-ht6 receptors.5-羟色胺6受体
Curr Drug Targets CNS Neurol Disord. 2004 Feb;3(1):59-79. doi: 10.2174/1568007043482561.
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Solution structure of intracellular signal-transducing peptide derived from human beta(2)-adrenergic receptor.
Biochem Biophys Res Commun. 2002 Mar 15;291(5):1297-301. doi: 10.1006/bbrc.2002.6606.
8
Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides.细胞穿透性膜锚定肽对G蛋白偶联受体的激活与抑制作用
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9
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10
An improved method for the preparation of synaptosomal fractions in high purity.
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