Maggini S, Wenzlaff S, Hornig D
Bayer Consumer Care Ltd, Basel, Switzerland.
J Int Med Res. 2010 Mar-Apr;38(2):386-414. doi: 10.1177/147323001003800203.
With the progressive elimination of dietary protein-energy deficits, deficiencies of micronutrients are emerging as the limiting factors in ensuring children's optimal health. Data from several countries in Asia and Latin America indicate that deficiencies of vitamin C and zinc continue to be at alarming levels. This article reviews the roles of vitamin C and zinc in supporting children's growth and development, with a particular focus on the complementary roles they play in supporting immune functions and combating infections. The contemporary relevance of vitamin C and zinc deficiency in the Asian and Latin American regions, both undergoing a rapid nutritional transition, are also discussed. Overall, there is increasing evidence that deficiency of vitamin C and zinc adversely affects the physical and mental growth of children and can impair their immune defences. Nutrition should be the main vehicle for providing these essential nutrients; however, supplementation can represent a valid support method, especially in developing regions.
随着膳食蛋白质 - 能量缺乏状况的逐步消除，微量营养素缺乏正成为确保儿童最佳健康状态的限制因素。来自亚洲和拉丁美洲几个国家的数据表明，维生素C和锌的缺乏程度仍然令人担忧。本文回顾了维生素C和锌在支持儿童生长发育方面的作用，特别关注它们在支持免疫功能和对抗感染方面所发挥的互补作用。同时也讨论了维生素C和锌缺乏在亚洲和拉丁美洲地区的当代相关性，这两个地区都正在经历快速的营养转型。总体而言，越来越多的证据表明，维生素C和锌的缺乏会对儿童的身心发育产生不利影响，并可能损害其免疫防御能力。营养应是提供这些必需营养素的主要途径；然而，补充剂也可以是一种有效的支持方法，特别是在发展中地区。
