Miyakawa H, Matsumoto K, Matsumoto S, Kinoshita R, Noguchi T, Taniguchi K, Honda N
Department of Anesthesiology, Medical College of Oita.
Masui. 1991 Jan;40(1):119-23.
Anesthesia and postoperative management of a patient with Gilbert's syndrome and one with Dubin-Johnson syndrome is reported. The former patient underwent open heart surgery and the latter had a partial resection and reconstruction of the esophagus. The anesthetics used in these two cases were fentanyl and nitrous oxide. The patient with Gilbert's syndrome had remarkable perioperative complications. On the other hand, the patient with Dubin-Johnson syndrome developed conjugated hyperbilirubinemia after the 2nd postoperative day. On the 5th postoperative day, his serum and direct bilirubin levels were elevated to 19.3 mg.dl-1 and 12.8 mg.dl-1, respectively. Therefore, we had to perform daily plasmapheresis on this patient for four days. Thereafter, his serum bilirubin level decreased gradually.
报告了1例吉尔伯特综合征患者和1例杜宾-约翰逊综合征患者的麻醉及术后管理情况。前1例患者接受了心脏直视手术，后1例患者进行了食管部分切除及重建手术。这两例患者使用的麻醉剂为芬太尼和氧化亚氮。吉尔伯特综合征患者围手术期出现了显著并发症。另一方面，杜宾-约翰逊综合征患者术后第2天出现结合胆红素血症。术后第5天，其血清胆红素和直接胆红素水平分别升高至19.3mg·dl⁻¹和12.8mg·dl⁻¹。因此，我们不得不对该患者连续4天每天进行血浆置换。此后，其血清胆红素水平逐渐下降。
