Cardiothoracic Surgery Department, Theagenio Cancer Hospital, Thessaloniki, Greece.
Hellenic J Cardiol. 2010 May-Jun;51(3):214-8.
Of oncological patients who have undergone chest radiation therapy, 20% develop radiation-induced constrictive pericarditis. The purpose of this study was to review our clinic's experience of such cases, focusing on survival and the functional outcome.
Six patients with a history of previous radiation therapy, aged 33-61 years, most of whom had symptoms of heart failure, underwent radical (2 patients) or partial (4 patients) pericardiectomy.
All patients were completely free of cardiovascular events during the 8 years covered by the study. Among the postoperative complications the most serious was low cardiac output syndrome in 4 patients, which was treated successfully.
Radiation-induced constrictive pericarditis is a clinical entity that should be taken into account in the differential diagnosis of oncological patients who show signs of heart failure. Surgery is the only effective treatment. The results are satisfactory, but always depend on associated damage to the myocardium as a result of radiation and on the underlying cancer.
在接受过胸部放射治疗的肿瘤患者中，有 20%会发生放射性缩窄性心包炎。本研究旨在回顾我们科室此类病例的经验，重点关注生存和功能结局。
6 名有既往放射治疗史的患者，年龄 33-61 岁，大多数有心力衰竭症状，接受了根治性（2 例）或部分（4 例）心包切除术。
所有患者在研究涵盖的 8 年内均无心血管事件。术后并发症中最严重的是 4 例低心输出量综合征，经成功治疗。
放射性缩窄性心包炎是一种临床实体，在表现出心力衰竭迹象的肿瘤患者的鉴别诊断中应考虑到这一点。手术是唯一有效的治疗方法。结果令人满意，但始终取决于放射引起的心肌损伤和基础癌症。
