Nakai Y, Kataoka Y, Bandho M, Itoh K, Hiasa Y, Wada T, Ootani R, Tabata T, Shinohara H, Aihara T
Department of Cardiology, Komatsushima Red Cross Hospital.
Kyobu Geka. 1991 May;44(5):373-9.
In an effort to improve the operative outcome in severe valvular heart disease, we investigated the effects of low-dose infusion of dopamine and dobutamine up to the day of operation. New York Heart Association Functional Class was improved significantly before operation, as compared with at the time of admission. It was possible to perform operation on individual patients when their physical condition seemed to be at their best. In patients with fear of postoperative renal failure, hemodialysis was combined during cardiac surgery to prevent failing to renal dysfunction after operation. As the result of these procedures, we were able to obtain satisfactory result. In patients with severe valvular heart disease, the preoperative combined infusion of dopamine and dobutamine, and hemodialysis during cardiac surgery to prevent postoperative renal dysfunction seemed to improve the operative outcome.
为改善重症瓣膜性心脏病的手术效果，我们研究了直至手术当日小剂量输注多巴胺和多巴酚丁胺的效果。与入院时相比，纽约心脏协会心功能分级在术前有显著改善。当个体患者身体状况处于最佳状态时，有可能对其进行手术。对于担心术后肾衰竭的患者，在心脏手术期间联合进行血液透析，以防止术后出现肾功能不全。通过这些措施，我们获得了满意的结果。在重症瓣膜性心脏病患者中，术前联合输注多巴胺和多巴酚丁胺，以及在心脏手术期间进行血液透析以预防术后肾功能不全，似乎可改善手术效果。
