Birmingham, United Kingdom From the Department of Plastic and Reconstructive Surgery, Sandwell and West Birmingham NHS Trust, City Hospital.
Plast Reconstr Surg. 2010 Jun;125(6):1615-1619. doi: 10.1097/PRS.0b013e3181d0ab4d.
The use of quilting sutures in the extended latissimus dorsi flap donor site significantly reduces the incidence of donor-site seroma. However, the donor site has a drain inserted, and the duration of use of this drain often dictates when a patient is discharged to home from the hospital. Fibrin glue has been shown to reduce the need for drainage at other operative sites. The authors therefore evaluated the use of fibrin glue (Tisseel Lyo; Baxter Healthcare, Norfolk, United Kingdom) in addition to quilting in reducing the total volume and duration of drainage following extended latissimus dorsi flap breast reconstruction.
The authors compared a group of 11 consecutive, prospective patients who underwent extended latissimus dorsi donor-site closure with fibrin glue and quilting with a control group of 24 consecutive, retrospective patients who underwent extended latissimus dorsi donor-site closed with quilting alone.
The results show that the combination of fibrin glue and quilting in the extended latissimus dorsi flap donor site significantly reduces average drainage in the immediate postoperative period: 13 ml compared with 170 ml (p <or= 0.001); average total drainage, 330 ml compared with 645 ml (p = 0.018); and average drain stay, 4 days compared with 5 days (p = 0.022).
Fibrin glue potentially may reduce the numbers of days that drains are left in situ or even reduce the drainage to such a degree that drains are no longer necessary for patients undergoing extended latissimus dorsi-based breast reconstructions.
在延长背阔肌皮瓣供区使用缝合缝线可显著降低供区血清肿的发生率。然而,供区需要插入引流管,引流管的使用时间通常决定了患者从医院出院回家的时间。纤维蛋白胶已被证明可减少其他手术部位的引流需求。因此,作者评估了在延长背阔肌皮瓣乳房重建中使用纤维蛋白胶(Tisseel Lyo;Baxter Healthcare,Norfolk,英国)联合缝合缝线以减少引流总量和持续时间。
作者比较了一组连续的 11 例前瞻性患者,他们接受了纤维蛋白胶和缝合缝线的联合治疗,用于延长背阔肌供区的闭合,以及一组连续的 24 例回顾性患者,他们接受了单纯缝合缝线的延长背阔肌供区闭合。
结果表明,在延长背阔肌皮瓣供区使用纤维蛋白胶和缝合缝线联合治疗可显著减少术后即刻的平均引流量:13ml 比 170ml(p<0.001);平均总引流量,330ml 比 645ml(p=0.018);以及平均引流管留置时间,4 天比 5 天(p=0.022)。
纤维蛋白胶可能会减少引流管原位留置的天数,甚至可以减少引流程度,使接受延长背阔肌皮瓣乳房重建的患者不再需要引流。