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[环孢素在寻常型天疱疮治疗中的效用。附3例报告]

[Usefulness of cyclosporin in the treatment of pemphigus vulgaris. Apropos of 3 cases].

作者信息

Castro-Salomó A, Porcel J M, Ordi J, Martínez-Costa X, Vilardell M, Vidal J

机构信息

Servicio de Medicina Interna, Hospital General Vall d'Hebron, Universidad Autónoma, Barcelona.

出版信息

Med Clin (Barc). 1991 Apr 27;96(16):619-20.

PMID:2051832
Abstract

Cyclosporin is a useful drug in several autoimmune diseases. It has been recently evaluated, with varying results, in several dermatoses such as pemphigus vulgaris. Three cases of this condition treated with cyclosporin are reported. The drug permitted to reduce and then to suppress prolonged corticosteroid therapy, and remission was maintained after exacerbation even in monotherapy. Hypertrichosis and gum hypertrophy were the common adverse effects.

摘要

环孢素在多种自身免疫性疾病中是一种有用的药物。最近它在几种皮肤病如寻常型天疱疮中得到评估,结果各异。本文报道了3例用环孢素治疗该疾病的病例。该药能够减少并随后停用长期的皮质类固醇治疗,即使在单一疗法中,病情加重后缓解仍能维持。多毛症和牙龈增生是常见的不良反应。

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