Fenske Neil Alan, Spencer James, Adam Friedman
University of South Florida College of Medicine,Tampa, FL, USA.
J Drugs Dermatol. 2010 May;9(5 Suppl ODAC Conf Pt 1):s45-9.
Actinic keratoses (AKs) are cutaneous neoplasms composed of proliferations of cytologically aberrant, epidermal keratinocytes caused by prolonged exposure to ultraviolet radiation. Combining the evidence that AKs are the second most common reason for visits to the dermatologist and it is generally believed that they should be treated, it is no surprise that the direct cost of the management of actinic keratoses in the United States (U.S.) is exceedingly high. There are currently numerous treatment modalities with more on the way as there is a demand for formulating newer, cheaper, less painful and less invasive means. The future of AK treatment involves both the continued investigation of current novel therapies, as well as the development of new treatment modalities.
光化性角化病（AKs）是一种皮肤肿瘤，由长期暴露于紫外线辐射导致的细胞学异常的表皮角质形成细胞增殖组成。鉴于AKs是皮肤科医生问诊的第二大常见原因，且人们普遍认为应进行治疗，因此美国光化性角化病治疗的直接成本极高也就不足为奇了。目前有多种治疗方式，而且随着对更新、更便宜、痛苦更小且侵入性更小的治疗手段的需求，更多治疗方式也在不断涌现。AK治疗的未来既包括对当前新型疗法的持续研究，也包括新治疗方式的开发。
