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子宫内膜异位症的无创诊断:是目标还是乌龙球?

Non-invasive diagnosis of endometriosis: the goal or own goal?

机构信息

Department of Obstetrics, Gynecology and Neonatology, Fondazione Ospedale Maggiore Policlinico, Mangiagalli and Regina Elena, Milan, Italy.

出版信息

Hum Reprod. 2010 Aug;25(8):1863-8. doi: 10.1093/humrep/deq141. Epub 2010 Jun 2.

DOI:10.1093/humrep/deq141
PMID:20519246
Abstract

Laparoscopy is the gold standard for the diagnosis of endometriosis. Although some forms of the disease, such as ovarian endometriomas or deep infiltrating lesions, can now be reliably diagnosed using non-invasive instruments, adhesions and superficial implants cannot be identified without surgery. Identification of these latter forms of the disease has been the main rationale for claiming the necessity to identify non-invasive diagnostic tests to detect endometriosis. In this opinion paper, we analyse the pros and cons of the availability of this kind of test in the current context of our knowledge of the disease. In particular, we emphasize that this instrument may be of benefit provided that the test is not used as a screening test.

摘要

腹腔镜检查是诊断子宫内膜异位症的金标准。虽然现在可以使用非侵入性仪器可靠地诊断某些形式的疾病,如卵巢子宫内膜异位囊肿或深部浸润性病变,但如果不进行手术,粘连和浅表植入物就无法识别。这些疾病的后一种形式的识别一直是主张有必要确定非侵入性诊断测试以检测子宫内膜异位症的主要理由。在本意见文中,我们分析了在我们对疾病的现有认识的背景下,这种测试的优缺点。特别是,我们强调指出,只有在不将该测试用作筛查测试的情况下,该仪器才可能有益。

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1
Non-invasive diagnosis of endometriosis: the goal or own goal?子宫内膜异位症的无创诊断:是目标还是乌龙球?
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引用本文的文献

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Ovarian damage following surgery for endometriomas, 20 years later: did awareness improve the situation?子宫内膜异位囊肿手术后20年的卵巢损伤:认知的提高改善了这种情况吗?
Arch Gynecol Obstet. 2025 May 16. doi: 10.1007/s00404-025-08039-x.
2
Use of the Free Endometriosis Risk Advisor App as a Non-Invasive Screening Test for Endometriosis in Patients with Chronic Pelvic Pain and/or Unexplained Infertility.使用免费的子宫内膜异位症风险评估应用程序作为慢性盆腔疼痛和/或不明原因不孕症患者子宫内膜异位症的非侵入性筛查测试。
J Clin Med. 2023 Aug 11;12(16):5234. doi: 10.3390/jcm12165234.
3
Translational Applications of Linear and Circular Long Noncoding RNAs in Endometriosis.
线性和环状长非编码 RNA 在子宫内膜异位症中的转化应用。
Int J Mol Sci. 2021 Sep 30;22(19):10626. doi: 10.3390/ijms221910626.
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Overview of miRNAs for the non-invasive diagnosis of endometriosis: evidence, challenges and strategies. A systematic review.miRNAs 用于子宫内膜异位症非侵入性诊断的概述:证据、挑战与策略。系统评价。
Einstein (Sao Paulo). 2021 Apr 26;19:eRW5704. doi: 10.31744/einstein_journal/2021RW5704. eCollection 2021.
5
Biomarkers of Pelvic Endometriosis.盆腔子宫内膜异位症的生物标志物
Rev Bras Ginecol Obstet. 2017 Mar;39(3):91-93. doi: 10.1055/s-0037-1601398. Epub 2017 Mar 30.
6
Endometriomas and deep infiltrating endometriosis in adulthood are strongly associated with anogenital distance, a biomarker for prenatal hormonal environment.成年期的子宫内膜异位囊肿和深部浸润性子宫内膜异位症与肛殖距密切相关,肛殖距是一种产前激素环境的生物标志物。
Hum Reprod. 2016 Oct;31(10):2377-83. doi: 10.1093/humrep/dew163. Epub 2016 Jun 28.
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Patients' and physicians' descriptions of occurrence and diagnosis of endometriosis: a qualitative study from Iran.患者与医生对子宫内膜异位症发生及诊断的描述:一项来自伊朗的定性研究
BMC Womens Health. 2014 Aug 30;14:103. doi: 10.1186/1472-6874-14-103.
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Endometriosis: pathogenesis and treatment.子宫内膜异位症:发病机制与治疗。
Nat Rev Endocrinol. 2014 May;10(5):261-75. doi: 10.1038/nrendo.2013.255. Epub 2013 Dec 24.
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