Georghiou Georgios P, Vidne Bernardo A, Sahar Gideon, Sharoni Erez, Fuks Avi, Porat Eyal
Department of Cardiothoracic Surgery, Rabin Medical Center, Beilinson Campus, Petah Tiqwa and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Asian Cardiovasc Thorac Ann. 2010 Jun;18(3):226-8. doi: 10.1177/0218492310367522.
To assess the prevalence, characteristics, and outcome of surgical treatment of primary cardiac valve tumors in a single center, we reviewed our experience in 6 women and 1 man, aged 49 to 76 years (mean, 64.7 years) who presented between 1999 and 2006. In one patient, the diagnosis of cardiac valve tumor was made incidentally on transesophageal echocardiography during aortocoronary bypass surgery. The others had clinical symptoms: angina or myocardial infarction in 3, congestive heart failure in 2, dyspnea and cerebrovascular ischemia in 1 patient each. Four of the 7 tumors were benign, and 3 were malignant. All patients survived the operation and recovered uneventfully. Midterm follow-up was available in all patients. Two patients with malignant tumors were considered unsuitable for adjuvant therapy by the oncologist; both died during follow-up from local tumor recurrence. All 5 survivors were categorized at the last follow-up as functional class I, with normal exercise tolerance. Excellent early and midterm surgical results can be obtained in patients with benign cardiac valve tumors, but the prognosis for those with a malignant tumor is poor.
为评估单中心原发性心脏瓣膜肿瘤手术治疗的患病率、特征及结果，我们回顾了1999年至2006年间6名女性和1名男性（年龄49至76岁，平均64.7岁）的治疗经验。其中1例患者在主动脉冠状动脉搭桥手术期间经食管超声心动图偶然诊断为心脏瓣膜肿瘤。其他患者有临床症状：3例为心绞痛或心肌梗死，2例为充血性心力衰竭，1例为呼吸困难和脑血管缺血。7例肿瘤中4例为良性，3例为恶性。所有患者术后存活且恢复顺利。所有患者均有中期随访。肿瘤学家认为2例恶性肿瘤患者不适合辅助治疗；二者均在随访期间因局部肿瘤复发死亡。最后一次随访时，所有5名幸存者均归类为心功能I级，运动耐量正常。良性心脏瓣膜肿瘤患者可获得良好的早期和中期手术结果，但恶性肿瘤患者预后较差。
