马来酸哌克昔林所致的水肿性视神经病变伴周围性多发性神经病（作者译）
[Oedematous optic neuropathy from Perhexilline maleate associated with peripheral polyneuropathy (author's transl)].
作者信息
van Effenterre R, Poisson M, van Effenterre G, Schaison M, Sichez J P, Haut J
出版信息
Arch Ophtalmol (Paris). 1977;37(11):709-14.
PMID:205202
Abstract
The authors report on a polyradiculoneuropathy related to long-term treatment with Perhexiline maleate (a drug used in France since 1973 for coronary insufficiency) whose presenting sign is a bilateral aedematous optic neuropathy. The mechanism of this effect on the optic nerves and on papilloedema is discussed; it seems not to be caused by a direct toxic action on the optic fibres but by the existence of chronic intracranial hypertension.
摘要
作者报告了一例与长期使用马来酸哌克昔林（1973年起在法国用于治疗冠状动脉供血不足的药物）相关的多神经根神经病，其表现体征为双侧水肿性视神经病变。文中讨论了这种对视神经和视乳头水肿的作用机制；其似乎并非由对视神经纤维的直接毒性作用引起，而是由慢性颅内高压导致。
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[Oedematous optic neuropathy from Perhexilline maleate associated with peripheral polyneuropathy (author's transl)].马来酸哌克昔林所致的水肿性视神经病变伴周围性多发性神经病（作者译）
Arch Ophtalmol (Paris). 1977;37(11):709-14.
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