Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City, USA.
Cornea. 2010 Sep;29(9):991-5. doi: 10.1097/ICO.0b013e3181cc7b02.
To determine the prevalence and risk factors for escalation of glaucoma therapy after deep lamellar endothelial keratoplasty (DLEK).
Retrospective review of every case of DLEK performed at a tertiary care facility between December 1, 2003 and January 31, 2006.
Eighty eyes met the inclusion criteria. Escalation of glaucoma therapy occurred in 13 eyes (16.3%) during a mean follow-up period of 27.1 months. Ten eyes required additional topical medical therapy, and 3 eyes required surgical intervention. Glaucoma therapy escalation was significantly associated with preexisting glaucoma (42.9% vs. 10.6%; P = 0.008).
Escalation of glaucoma therapy is not uncommon after DLEK, especially in eyes with preexisting glaucoma.
确定深板层角膜内皮移植术（DLEK）后青光眼治疗升级的患病率和危险因素。
回顾性分析 2003 年 12 月 1 日至 2006 年 1 月 31 日在一家三级保健机构进行的每例 DLEK 病例。
80 只眼符合纳入标准。在平均 27.1 个月的随访期间，13 只眼（16.3%）需要升级青光眼治疗。10 只眼需要额外的局部药物治疗，3 只眼需要手术干预。青光眼治疗升级与术前青光眼显著相关（42.9%比 10.6%；P=0.008）。
DLEK 后青光眼治疗升级并不少见，尤其是在术前有青光眼的眼中。
