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本文引用的文献

1
Attaining negative margins in breast-conservation operations: is there a consensus among breast surgeons?在保乳手术中实现切缘阴性:乳腺外科医生之间是否存在共识?
J Am Coll Surg. 2009 Nov;209(5):608-13. doi: 10.1016/j.jamcollsurg.2009.07.026. Epub 2009 Sep 11.
2
Ultrasound and fine needle aspiration cytology of the axilla in the pre-operative identification of axillary nodal involvement in breast cancer.乳腺癌腋窝淋巴结受累术前超声及细针穿刺细胞学检查对腋窝的评估
Eur J Surg Oncol. 2009 Nov;35(11):1152-7. doi: 10.1016/j.ejso.2009.03.008. Epub 2009 May 15.
3
First three sentinel lymph nodes accurately stage the axilla in breast cancer.最初的三个前哨淋巴结可准确判断乳腺癌腋窝分期。
Am Surg. 2009 Mar;75(3):253-6.
4
Effectiveness of immediate preoperative injection of radiopharmaceutical and blue dye for sentinel node biopsy in patients with breast cancer.乳腺癌患者术前即刻注射放射性药物和蓝色染料用于前哨淋巴结活检的有效性。
Eur J Cancer. 2009 Mar;45(5):795-9. doi: 10.1016/j.ejca.2008.11.011. Epub 2008 Dec 26.
5
Axillary lymph nodes suspicious for breast cancer metastasis: sampling with US-guided 14-gauge core-needle biopsy--clinical experience in 100 patients.怀疑有乳腺癌转移的腋窝淋巴结:超声引导下14号粗针活检取样——100例患者的临床经验
Radiology. 2009 Jan;250(1):41-9. doi: 10.1148/radiol.2493071483. Epub 2008 Oct 27.
6
Intraoperative radioisotope injection for sentinel lymph node biopsy.术中放射性同位素注射用于前哨淋巴结活检。
Ann Surg Oncol. 2008 Nov;15(11):3216-21. doi: 10.1245/s10434-008-0010-3. Epub 2008 Sep 6.
7
Internal mammary nodes in breast cancer: diagnosis and implications for patient management -- a systematic review.乳腺癌中的内乳淋巴结:诊断及其对患者管理的意义——一项系统评价
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8
Radiotherapy in Italy after conservative treatment of early breast cancer. A survey by the Italian Society of Radiation Oncology (AIRO).意大利早期乳腺癌保守治疗后的放射治疗。意大利放射肿瘤学会(AIRO)的一项调查。
Tumori. 2008 May-Jun;94(3):333-41. doi: 10.1177/030089160809400308.
9
Timing of sentinel lymph node biopsy in patients receiving neoadjuvant chemotherapy for breast cancer.接受新辅助化疗的乳腺癌患者前哨淋巴结活检的时机
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Distinct lymph nodal sonographic characteristics in breast cancer patients at high risk for axillary metastases correlate with the final axillary stage.具有腋窝转移高风险的乳腺癌患者独特的淋巴结超声特征与最终腋窝分期相关。
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英国乳腺癌患者腋窝手术管理的进一步调查。

A further survey of surgical management of the axilla in UK breast cancer patients.

作者信息

Glynn Ronan W, Williams Linda, Dixon J Michael

机构信息

Edinburgh Breast Unit, Western General Hospital, Edinburgh, UK.

出版信息

Ann R Coll Surg Engl. 2010 Sep;92(6):506-11. doi: 10.1308/003588410X12664192075819. Epub 2010 Jun 1.

DOI:10.1308/003588410X12664192075819
PMID:20522293
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3182795/
Abstract

INTRODUCTION

The aims of this study were to investigate the practice of axillary lymph node management within different units throughout the UK, and to assess changes in practice since our previous survey in 2004.

SUBJECTS AND METHODS

A structured questionnaire was sent to 350 members of the British Association of Surgical Oncology.

RESULTS

There were 177 replies from respondents who managed more than 100 patients a year with breast cancer. Of these: 12 did not perform axillary ultrasound at all in their centre; 17 (10%) employed axillary node clearance (ANC) on all patients; 122 (69%) performed sentinel node biopsy (SNB) with dual localisation; and 111 respondents had attended the New Start Course. Radioisotope was most frequently injected 2 h or more before operation. Just 13 surgeons were convinced of the value of dissecting internal mammary nodes visualised on a scan. Reasons for not using dual localisation included lack of nuclear medicine facilities, no local ARSAC licence holder, no probe, and no funding. Sixty-six surgeons stated that, if they had an ARSAC licence and could inject the radioactivity in theatre, this would be a major improvement. In addition, 83 (47%) did not perform SLNB in patients receiving neo-adjuvant chemotherapy.

CONCLUSIONS

Despite significant changes since 2004, substantial variation remains in management of the axilla. A number of surgeons are practicing outwith current guidelines.

摘要

引言

本研究的目的是调查英国不同单位腋窝淋巴结管理的实践情况,并评估自我们2004年上次调查以来实践中的变化。

研究对象与方法

向英国外科肿瘤学会的350名成员发送了一份结构化问卷。

结果

每年管理超过100例乳腺癌患者的受访者中有177份回复。其中:12人所在中心根本不进行腋窝超声检查;17人(10%)对所有患者采用腋窝淋巴结清扫术(ANC);122人(69%)进行双定位前哨淋巴结活检(SNB);111名受访者参加了新起点课程。放射性同位素最常在手术前2小时或更长时间注射。只有13名外科医生确信扫描显示的内乳淋巴结清扫的价值。不使用双定位的原因包括缺乏核医学设施、没有当地放射性物质咨询委员会(ARSAC)许可证持有者、没有探头和没有资金。66名外科医生表示,如果他们有ARSAC许可证并且可以在手术室注射放射性物质,这将是一个重大改进。此外,83人(47%)在接受新辅助化疗的患者中不进行前哨淋巴结活检。

结论

尽管自2004年以来有了显著变化,但腋窝管理仍存在很大差异。一些外科医生的做法不符合当前指南。