Debus Jürgen, Eberhardt Wilfried, Hoffmann Hans, Passlick Bernward, Rübe Christian, Thomas Michael
Abteilung Radioonkologie und Strahlentherapie, Radiologische Universitätsklinik Heidelberg, Heidelberg, Deutschland.
Onkologie. 2010;33 Suppl 5:12-20. doi: 10.1159/000313972. Epub 2010 May 14.
Local interventions improve the prognosis of patients with non-small-cell lung cancer (NSCLC) and can, in many cases, enable long-term survival. This is not just true for early-stage patients but also for selected patients with operable singular intra- or extrathoracic metastases. This article focuses on the use of bimodal treatment in stage IIIA/IIIB disease, exploration of the mediastinum, trimodal therapy in the case of patients with N2 disease identified prior to treatment, curative resection in metastatic disease, and the use of stereotactic radiation therapy in NSCLC.
局部干预可改善非小细胞肺癌(NSCLC)患者的预后,并且在许多情况下可实现长期生存。这不仅适用于早期患者,也适用于某些具有可手术的单个胸内或胸外转移灶的患者。本文重点介绍ⅢA/ⅢB期疾病的双峰治疗、纵隔探查、治疗前确诊为N2期疾病患者的三联疗法、转移性疾病的根治性切除以及NSCLC中立体定向放射治疗的应用。