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低温循环停搏或体外循环时间延长是否会影响再次主动脉手术的早期预后?

Does hypothermic circulatory arrest or prolonged cardiopulmonary bypass time affect early outcome in reoperative aortic surgery?

作者信息

Chamogeorgakis T P, Anagnostopoulos C E, Kostopanagiotou G, Angouras D C, Toumpoulis I K, Matiatou S, Georgiannakis M C, Mallios D, Rokkas C K

机构信息

Department of Cardiothoracic Surgery, University of Athens School of Medicine, "Attikon" Hospital Center, Athens, Greece.

出版信息

J Cardiovasc Surg (Torino). 2010 Jun;51(3):423-8.

Abstract

AIM

Prolonged cardio-pulmonary bypass (CPB) time, usually necessary for reoperations, is known to increase mortality in coronary bypass procedures and aortic reoperations. We investigated if prolonged CPB time and arch reconstruction in reoperations of the thoracic aorta affect in-hospital outcome.

METHODS

Twenty-nine patients underwent reoperations on the thoracic aorta. The reoperations performed were aortic root replacement with composite graft without aortic arch involvement in ten patients, isolated ascending aorta replacement in six patients, aortic arch replacement as a primary procedure in two patients, and aortic arch in conjunction with ascending or descending aorta replacement in 11 patients.

RESULTS

Fourteen patients had aortic reoperation with deep hypothermic circulatory arrest (DHCA) and 15 without DHCA. The in-hospital mortality rate was 13.8%. The use deep hypothermic circulatory arrest or CPB time did not affect early outcome. Previous coronary artery bypass procedure was independent predictor of in-hospital mortality. Seven patients required re-exploration for bleeding. One patient suffered from stroke and finally five patients had prolonged ventilation, two requiring tracheostomy. There have been no deaths in the follow-up period. None of the patients has required repeat surgical intervention on the heart or the aorta.

CONCLUSION

The use of DHCA or prolonged CPB time do not affect early outcome in reoperations of the thoracic aorta.

摘要

目的

已知再次手术通常所需的长时间体外循环(CPB)会增加冠状动脉搭桥手术和主动脉再次手术的死亡率。我们研究了在胸主动脉再次手术中延长CPB时间和主动脉弓重建是否会影响住院结局。

方法

29例患者接受了胸主动脉再次手术。所进行的再次手术包括10例采用复合移植物进行主动脉根部置换且未累及主动脉弓,6例进行单纯升主动脉置换,2例将主动脉弓置换作为主要手术,11例将主动脉弓与升主动脉或降主动脉置换联合进行。

结果

14例患者在深低温停循环(DHCA)下进行主动脉再次手术,15例未采用DHCA。住院死亡率为13.8%。使用深低温停循环或CPB时间并不影响早期结局。既往冠状动脉搭桥手术是住院死亡率的独立预测因素。7例患者因出血需要再次开胸探查。1例患者发生卒中,最终5例患者通气时间延长,2例需要气管切开。随访期间无死亡病例。所有患者均无需对心脏或主动脉进行再次手术干预。

结论

在胸主动脉再次手术中使用DHCA或延长CPB时间并不影响早期结局。

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