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顶叶皮质下卒中后丘脑痛消失

Disappearance of thalamic pain after parietal subcortical stroke.

作者信息

Soria Emilio D, Fine Edward J

机构信息

Department of Neurology, State University of New York, Buffalo, NYU.S.A. Veterans Administration Medical Center, Buffalo, NYU.S.A.

出版信息

Pain. 1991 Mar;44(3):285-288. doi: 10.1016/0304-3959(91)90098-I.

DOI:10.1016/0304-3959(91)90098-I
PMID:2052398
Abstract

A hypertensive man had a long standing history of contumacious hyperpathia in the right upper extremity, resistant to medical therapy, secondary to a lacunar infarct in the left thalamus. A second cerebrovascular accident caused a small lesion in the left corona radiata, interrupting the thalamoparietal interconnections, and terminated the pain instantly. Interruption of the subcortical parietal white matter may more effectively control pain than cortical lesions. A few surgeons have successfully treated rebellious chronic pain with stereotaxic operations in the corona radiata, resulting in lesions very similar to our patient's. This overlooked and nearly forgotten technique may still have value in treating selected cases.

摘要

一名高血压患者长期存在右上肢顽固性痛觉过敏,药物治疗无效,病因是左侧丘脑腔隙性梗死。第二次脑血管意外在左侧放射冠造成一个小病灶,中断了丘脑与顶叶的联系,疼痛随即消失。中断皮质下顶叶白质可能比皮质病变更有效地控制疼痛。一些外科医生通过立体定向手术成功治疗了放射冠部位难治性慢性疼痛,造成的病灶与我们患者的非常相似。这种被忽视且几乎被遗忘的技术在治疗某些特定病例时可能仍有价值。

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引用本文的文献

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Brain Stimulation Therapy for Central Post-Stroke Pain from a Perspective of Interhemispheric Neural Network Remodeling.从半球间神经网络重塑角度看脑刺激疗法治疗中风后中枢性疼痛
Front Hum Neurosci. 2016 Apr 21;10:166. doi: 10.3389/fnhum.2016.00166. eCollection 2016.
2
Modulating the pain network--neurostimulation for central poststroke pain.调节疼痛网络 - 神经刺激治疗脑卒中后中枢性疼痛。
Nat Rev Neurol. 2015 May;11(5):290-9. doi: 10.1038/nrneurol.2015.58. Epub 2015 Apr 21.
3
Pharmacological management of central post-stroke pain: a practical guide.
中风后中枢性疼痛的药物治疗:实用指南。
CNS Drugs. 2014 Sep;28(9):787-97. doi: 10.1007/s40263-014-0194-y.
4
Altered pain and thermal sensation in subjects with isolated parietal and insular cortical lesions.孤立顶叶和岛叶皮质病变患者的疼痛和温度感觉改变。
Eur J Pain. 2010 May;14(5):535.e1-11. doi: 10.1016/j.ejpain.2009.10.002. Epub 2009 Nov 25.
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Lesions limited to the human thalamic principal somatosensory nucleus (ventral caudal) are associated with loss of cold sensations and central pain.局限于人类丘脑主要体感核(尾侧腹核)的损伤与冷觉丧失和中枢性疼痛有关。
J Neurosci. 2007 May 2;27(18):4995-5004. doi: 10.1523/JNEUROSCI.0716-07.2007.
6
From thalamic syndrome to central poststroke pain.从丘脑综合征到脑卒中后中枢性疼痛。
J Neurol Neurosurg Psychiatry. 1996 Dec;61(6):560-4. doi: 10.1136/jnnp.61.6.560.