Sobhonslidsuk Abhasnee, Intaraprasong Pongphob, Tongprasert Sasinee
Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
J Med Assoc Thai. 2010 May;93(5):637-41.
Liver transplantation has been the last resort of definite treatment for decompensate cirrhosis, early-stage of hepatocellular carcinoma, and acute liver failure. Organ shortage is the major obstacle of deceased-donor liver transplantation. Since the first case of living-donor liver transplantation (LDLT), many centers around the world started the LDLT program. Living donors should be informed about the possible risk of morbidity and mortality, and later give consent for liver donation without coercion. Donor selection and evaluation have become one of the important steps prior to LDLT, aiming to exclude donors who may have high risks from LDLT and to assure that LDLT recipients will receive perfect liver grafts. In Thailand, living donors must have been blood relatives or be legally married with recipients for at least three years. Donor evaluation can be divided into three step-by-step phases. Psychological evaluation of living donors is also included in pre-transplant assessment.
肝移植一直是失代偿期肝硬化、早期肝细胞癌和急性肝衰竭确定性治疗的最后手段。器官短缺是尸体供肝肝移植的主要障碍。自首例活体供肝肝移植（LDLT）以来，世界各地的许多中心都启动了LDLT项目。应告知活体供体可能存在的发病和死亡风险，随后在无胁迫的情况下给予肝捐赠同意。供体选择和评估已成为LDLT之前的重要步骤之一，旨在排除可能存在高风险的LDLT供体，并确保LDLT受者能够获得完美的肝移植物。在泰国，活体供体必须是血亲或与受者合法结婚至少三年。供体评估可分为三个逐步阶段。活体供体的心理评估也包括在移植前评估中。
