Anastasi S, Caruso V, Magnano C, Leocata A
Divisione di Pediatria, Ospedale Garibaldi USL 34, Catania, Italia.
Pediatr Med Chir. 1991 Jan-Feb;13(1):63-5.
Based on a review of the literature and personal observation, the authors discuss the most frequent endocrine complication that occur in patients with thalassemia major given blood transfusion and chelating therapy. All the complication are attributed to iron overload in the endocrine glands. The authors conclude that an adequate chelating therapy protects against hemosiderosis and thus against endocrine pathologies.
基于文献综述和个人观察，作者讨论了重型地中海贫血患者在接受输血和螯合治疗时最常见的内分泌并发症。所有这些并发症都归因于内分泌腺的铁过载。作者得出结论，充分的螯合治疗可预防血色素沉着症，从而预防内分泌疾病。
