School of Biological Sciences, Monash University, Clayton, 3800 Victoria, Australia.
Am Nat. 2010 Aug;176(2):131-40. doi: 10.1086/653671.
Recent studies have uncovered an abundance of nonneutral cytoplasmic genetic variation within species, which suggests that we should no longer consider the cytoplasm an idle intermediary of evolutionary change. Nonneutrality of cytoplasmic genomes is particularly intriguing, given that these genomes are maternally transmitted. This means that the fate of any given cytoplasmic genetic mutation is directly tied to its performance when expressed in females. For this reason, it has been hypothesized that cytoplasmic genes will coevolve via a sexually antagonistic arms race with the biparentally transmitted nuclear genes with which they interact. We assess this prediction, examining the intergenomic contributions to the costs and benefits of mating in Callosobruchus maculatus females subjected to a mating treatment with three classes (kept virgin, mated once, or forced to cohabit with a male). We find no evidence that the economics of mating are determined by interactions between cytoplasmic genes expressed in females and nuclear genes expressed in males and, therefore, no support for a sexually antagonistic intergenomic arms race. The cost of mating to females was, however, shaped by an interaction between the cytoplasmic and nuclear genes expressed within females. Thus, cytonuclear interactions are embroiled in the economics of mating.
最近的研究揭示了物种内部细胞质遗传变异的丰富性，这表明我们不应该再将细胞质视为进化变化的消极媒介。细胞质基因组的非中性特别有趣，因为这些基因组是通过母系遗传的。这意味着任何给定的细胞质基因突变的命运都与其在雌性中表达时的表现直接相关。因此，人们假设细胞质基因将通过与它们相互作用的双亲遗传的核基因之间的性拮抗军备竞赛共同进化。我们通过检查 Callosobruchus maculatus 雌性在经历三种交配处理（保持处女、交配一次或被迫与雄性同居）后交配的成本和收益的基因组间贡献来评估这一预测。我们没有发现证据表明交配的经济学是由雌性中表达的细胞质基因和雄性中表达的核基因之间的相互作用决定的，因此，也没有支持性拮抗基因组间军备竞赛的证据。然而，雌性交配的成本是由雌性中表达的细胞质和核基因之间的相互作用决定的。因此，细胞质-核相互作用卷入了交配的经济学。
