Cleavage of native type III collagen in the collagenase susceptible region by thermolysin.
作者信息
Wang H M, Chan J, Pettigrew D W, Sodek J
出版信息
Biochim Biophys Acta. 1978 Mar 28;533(1):270-7. doi: 10.1016/0005-2795(78)90571-8.
PMID:205266
Abstract
Viscometric assays were used to demonstrate the activity of thermolysin (EC 3.4.24.4) on native type III collagen in solution. Analysis of the reaction products by sodium dodecyl sulphate-polyacrylamide gel electrophoresis and electron microscopic visualisation of segment long spacing aggregates demonstrated localised cleavage of the collagen in the collagenase susceptible region.
摘要
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Cleavage of native type III collagen in the collagenase susceptible region by thermolysin.
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