Shaikh Ayaz Hussain, Hanif Bashir, Adil Amina, Hashmani Shahrukh, Qazi Hammad Ali, Mujtaba Iqbal
Tabba Heart Institute, Karachi.
J Pak Med Assoc. 2010 May;60(5):374-6.
To determine the doppler derived mean gradients of St Jude mechanical prosthesis in early postoperative period in patients undergoing valve replacement at a tertiary care cardiac centre.
Medical records of 190 consecutive patients who underwent 233 mitral, aortic or dual (mitral and aortic) valve replacement by St Jude bileaflet mechanical prosthesis at Tabba Heart Institute, between March 2006 to December 2008 were reviewed. Doppler derived mean gradients were assessed predischarge and recorded.
There were 98 (51.5%) males and 92 (48.5%) females in the study cohort. The mean age was 40 +/- 14 years. Of the total, 101 (53%) had mitral, 46 (24.2%) had aortic and 43 (22.6%) patients had dual valve replacement. Doppler derived mean gradient was assessed across 144 mitral and 89 aortic St Jude mechanical prosthesis. Doppler derived mean gradient for St Jude mitral prosthesis was 3.5 mm Hg and for St Jude aortic prosthesis was 10.2 mm Hg.
The study determines baseline gradients across mitral and aortic St Jude mechanical prosthesis in our population. These can be used as reference gradients to assess St Jude prosthetic valve function in patients who did not have early postoperative doppler assessment.
确定在一家三级心脏护理中心接受瓣膜置换术的患者术后早期，圣犹达机械瓣膜的多普勒衍生平均梯度。
回顾了2006年3月至2008年12月期间在塔巴心脏研究所连续190例接受圣犹达双叶机械瓣膜二尖瓣、主动脉瓣或双瓣（二尖瓣和主动脉瓣）置换术患者的病历。在出院前评估并记录多普勒衍生平均梯度。
研究队列中有98名（51.5%）男性和92名（48.5%）女性。平均年龄为40±14岁。其中，101例（53%）为二尖瓣置换，46例（24.2%）为主动脉瓣置换，43例（22.6%）为双瓣置换。对144个二尖瓣和89个主动脉瓣圣犹达机械瓣膜进行了多普勒衍生平均梯度评估。圣犹达二尖瓣瓣膜的多普勒衍生平均梯度为3.5mmHg，圣犹达主动脉瓣瓣膜为10.2mmHg。
本研究确定了我们人群中二尖瓣和主动脉瓣圣犹达机械瓣膜的基线梯度。这些可作为参考梯度，用于评估术后早期未进行多普勒评估患者的圣犹达人工瓣膜功能。
