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后部可逆性脑病综合征:子痫患者的病例系列

Posterior reversible encephalopathy syndrome: a case series in patients with eclampsia.

作者信息

Naqi Rohana, Ahsan Humera, Azeemuddin Muhammad

机构信息

Radiology Department, Aga Khan University Hospital, Karachi.

出版信息

J Pak Med Assoc. 2010 May;60(5):394-7.

Abstract

Posterior Reversible Encephalopathy Syndrome (PRES) refers to a clinicoradiologic entity with characteristic features on neuro-imaging and non-specific symptoms comprising headache, confusion, visual disturbances and seizures. The lesions in PRES are thought to be due to vasogenic oedema, predominantly in the posterior cerebral hemispheres, and are reversible with appropriate management. We report 3 cases of acute PRES who had eclampsia and presented with recurrent episodes of seizures and hypertension. Their MRI scan showed diffuse abnormal signal intensities involving predominantly deep white matter of the occipital lobes. Based on the findings the most probable diagnosis of PRES was suggested. They were started on antihypertensive drugs. On follow-up examination after 5-7 weeks, the patients showed marked improvement clinically and on neuro-imaging following which they were discharged in stable condition.

摘要

后部可逆性脑病综合征(PRES)是一种临床放射学实体,具有神经影像学特征性表现以及包括头痛、意识模糊、视觉障碍和癫痫发作等非特异性症状。PRES中的病变被认为是由血管源性水肿引起的,主要累及大脑后半球,经适当治疗后可逆转。我们报告3例患有子痫并出现反复癫痫发作和高血压的急性PRES患者。他们的MRI扫描显示弥漫性异常信号强度,主要累及枕叶深部白质。基于这些发现,提示了PRES最可能的诊断。他们开始使用抗高血压药物治疗。在5 - 7周后的随访检查中,患者临床症状和神经影像学均显示明显改善,随后病情稳定出院。

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