Johnson C R, Shepherd R E
Bioinorg Chem. 1978;8(2):115-32. doi: 10.1016/s0006-3061(00)80238-0.
Esr and electronic spectra of complexes of the general composition VO(AA)2 and VO(ox)(AA) have been characterized; AA = gly, his, cys, pro, val, met, asp amino acids. Spectra of the formulation VO(ox)(LL) (with LL = imidazole plus monodentate oxalate, histamine plus monodentate oxalate, histidine, cysteine, 4-imidazolepropionic acid, mercaptopropionic acid, ethylenediamine and ethanolamine) have been used to deduce a self-consistent assignment of AL, a ligand donor additivity constant contribution to the observed hyperfine splitting, Aiso. Values of AL are sensitive to inductive effects in the ligand structure. The solution structures and likely coordination geometries of VO(his)2, and VO(cys)22-- are discussed. The role of the imidazole moiety as a sigma donor and sulfhydryl sulfur as a pi acceptor is observed in VO(AA)2 and VO(ox)(AA) complexes.
已对一般组成为VO(AA)₂和VO(ox)(AA)的配合物的血沉棕黄层（ESR）和电子光谱进行了表征；AA = 甘氨酸、组氨酸、半胱氨酸、脯氨酸、缬氨酸、蛋氨酸、天冬氨酸等氨基酸。已利用VO(ox)(LL)（其中LL = 咪唑加单齿草酸盐、组胺加单齿草酸盐、组氨酸、半胱氨酸、4-咪唑丙酸、巯基丙酸、乙二胺和乙醇胺）的光谱来推导配体供体加和常数对观察到的超精细分裂Aiso的自洽归属。AL值对配体结构中的诱导效应敏感。讨论了VO(his)₂和VO(cys)₂²⁻的溶液结构和可能的配位几何形状。在VO(AA)₂和VO(ox)(AA)配合物中观察到咪唑部分作为σ供体和巯基硫作为π受体的作用。
