Verger C, Larpent L, Veniez G, Corvaisier B
Unité de dialyse péritonéale et service de biochimie, hôpital René-Dubos, Pontoise.
Rev Prat. 1991 Apr 21;41(12):1086-90.
Monitoring peritoneal permeability is indispensable to adjust the dialysis procedure to the characteristics of each individual patient and to detect and prevent the complications of peritoneal dialysis. Several monitoring techniques can be used, the simplest one being the most inaccurate. The authors consider that in routine practice the first alterations can be detected merely by measuring ultrafiltration. The next step is a single glucose assay after a 4-hour long contact. Evaluating the speed of diffusion of glucose and urea by means of four assays in two hours is an excellent compromise: the equilibration curves thus obtained can be summarized as the time required for the percentage of glucose absorption to be identical with the percentage of dialysate saturation in urea (APEX time).
监测腹膜通透性对于根据每位患者的特点调整透析程序以及检测和预防腹膜透析并发症而言不可或缺。可以使用多种监测技术，其中最简单的一种也是最不准确的。作者认为，在常规实践中，仅通过测量超滤就可以检测到最初的变化。下一步是在4小时接触后进行一次葡萄糖检测。通过在两小时内进行四次检测来评估葡萄糖和尿素的扩散速度是一个很好的折衷方法：由此获得的平衡曲线可以总结为葡萄糖吸收百分比与透析液中尿素饱和百分比相等所需的时间（APEX时间）。
