Department of Paediatrics, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark.
Acta Paediatr. 2010 Aug;99(8):1131-4. doi: 10.1111/j.1651-2227.2010.01885.x. Epub 2010 Jun 2.
To compare the decrease in total serum bilirubin (TSB) concentration during conventional phototherapy in infants treated in supine position exclusively versus infants alternated between exposure in supine and prone position every third hour. Moreover, to survey current practice patterns in two Scandinavian countries as far as alternating exposure.
A total of 112 infants with non-haemolytic hyperbilirubinaemia, but otherwise healthy, and a gestational age > or =33 weeks were randomized to one of the treatment groups. All infants received phototherapy for 24 h. TSB was measured at start of phototherapy and after 12 and 24 h of treatment. Questionnaires about routines for position changes in infants during phototherapy were sent to all 41 neonatal departments in Denmark and Norway.
No statistically significant differences in the decrease in TSB were observed between the two treatment groups: at 12 h of therapy, TSB decreased 32% in both groups and at 24 h 49% and 50%, respectively. In two-thirds of Danish and Norwegian departments, the infants were routinely turned during phototherapy, most often every third hours.
The decrease in TSB was not significantly associated with positioning of the infant during conventional phototherapy. Alternating exposure is widely practiced in Scandinavia but is unnecessary.
比较仰卧位常规光疗与每 3 小时仰卧位与俯卧位交替光疗对血清总胆红素（TSB）浓度下降的影响。此外，还调查了两个斯堪的纳维亚国家目前在交替暴露方面的实践模式。
共有 112 名非溶血性高胆红素血症但健康的、胎龄≥33 周的婴儿被随机分配到治疗组之一。所有婴儿均接受 24 小时光疗。在光疗开始时、治疗 12 小时和 24 小时测量 TSB。向丹麦和挪威的所有 41 个新生儿病房发送了关于光疗期间婴儿体位变化常规的问卷。
两组 TSB 下降无统计学差异：治疗 12 小时时，两组 TSB 分别下降 32%，治疗 24 小时时分别下降 49%和 50%。在三分之二的丹麦和挪威病房，婴儿在光疗期间通常会被常规翻身，通常每 3 小时一次。
TSB 的下降与婴儿在常规光疗期间的体位无关。交替暴露在斯堪的纳维亚地区广泛应用，但没有必要。
