Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Hyogo, Japan.
FEMS Microbiol Lett. 2010 Aug 1;309(1):35-42. doi: 10.1111/j.1574-6968.2010.02014.x. Epub 2010 May 14.
RodZ (YfgA) is a membrane protein well conserved among bacterial species and important in the determination of cell shape and motility, although the molecular mechanism involved is not well established. We have characterized a DeltarodZ mutant and show that defective peptidoglycan synthesis might be the primary effect of the deletion. A motile pseudorevertant of DeltarodZ isolated possessed a near rod-shaped cell morphology, indicating that RodZ is not absolutely required for the elongation of the lateral cell wall and the synthesis of functional flagella.
RodZ(YfgA)是一种在细菌物种中广泛保守的膜蛋白,对细胞形状和运动性的决定很重要,尽管其涉及的分子机制尚未得到很好的确定。我们已经对 DeltarodZ 突变体进行了特征描述,并表明肽聚糖合成缺陷可能是缺失的主要影响。分离得到的 DeltarodZ 运动性假回复突变体具有近似杆状的细胞形态,表明 RodZ 并非绝对需要侧细胞壁的伸长和功能性鞭毛的合成。