Clinic for Maxillofacial Surgery, University of Mainz, Augustusplatz 2, 55131 Mainz, Germany.
Head Face Med. 2010 Jun 7;6:8. doi: 10.1186/1746-160X-6-8.
Mandibular reconstruction by means of fibula transplants is the standard therapy for severe bone loss after subtotal mandibulectomy. Venous failure still represents the most common complication in free flap surgery. We present the injection of heparine into the arterial pedicle as modification of the revising both anastomoses in these cases and illustrate the application with a clinical case example.
Methods consist of immediate revision surgery with clot removal, heparin perfusion by direct injection in the arterial vessel of the pedicle, subsequent high dose low-molecular weight heparin therapy, and leeches. After 6 hours postoperatively, images of early flap recovery show first sings of recovery by fading livid skin color.
The application of this technique in a patient with venous thrombosis resulted in the complete recovery of the flap 60 hours postoperatively. Other cases achieved similar success without additional lysis Therapy or revision of the arterial anastomosis.
Rescue of fibular flaps is possible even in patients with massive thrombosis if surgical revision is done quickly.
腓骨移植进行下颌骨重建是下颌骨次全切除后严重骨缺损的标准治疗方法。游离皮瓣手术后静脉功能衰竭仍然是最常见的并发症。我们提出在这些情况下通过向动脉蒂内注射肝素来修改吻合口,并用一个临床病例进行说明。
方法包括立即进行清创术、直接向蒂的动脉血管内注射肝素、随后进行大剂量低分子肝素治疗和使用蚂蟥。术后 6 小时,早期皮瓣恢复的图像显示出皮肤颜色由青紫色消退的恢复迹象。
该技术在一名静脉血栓形成患者中的应用导致术后 60 小时皮瓣完全恢复。其他病例在不进行额外溶栓治疗或修改动脉吻合口的情况下也取得了类似的成功。
如果手术修正迅速,即使在发生严重血栓的患者中,也有可能挽救腓骨皮瓣。