Department of Ophthalmology, Hallym University Sacred Heart Hospital, Anyang-City, Gyeong-gi-Do, 431-070, Republic of Korea.
Br J Ophthalmol. 2010 Sep;94(9):1160-4. doi: 10.1136/bjo.2009.167817. Epub 2010 Jun 7.
To study the effect and long-term sustainability of part-time occlusion therapy for anisometropic amblyopia after 8 years of age.
A total of 41 anisometropic amblyopes aged > or =8 years were analysed. In six patients, best-corrected visual acuity (BCVA) of amblyopic eye improved more than two lines within 2 weeks of full-time spectacle wear. The remaining patients were assigned to perform part-time patching during out-of-school hours. Long-term results were assessed in patients who were observed over 1 year after the end of the treatment.
Among 35 patients, four dropped out, refusing further treatment, and one changed to atropine penalisation. The part-time patching schedule was completed in 30 patients. 90% of patients (27/30) complied well. Mean BCVA in the amblyopic eye improved significantly (p<0.001), and 96.7% of patients (29/30) achieved the final BCVA of 0.1 logMAR or better. In long-term results, 87% preserved the BCVA of 0.1 logMAR or better. None of four dropouts achieved the BCVA of 0.1 logMAR or better in long-term results even on the continuous spectacle wear.
The part-time occlusion treatment in school-aged amblyopes, which had been carried out after school hours, was successful and the effect was sustained in most cases.
研究 8 岁以上屈光不正性弱视患者部分时间遮盖治疗的效果及长期可持续性。
对 41 例年龄>8 岁的屈光不正性弱视患者进行分析。6 例患者在全矫镜佩戴 2 周内，弱视眼最佳矫正视力（BCVA）提高超过两行。其余患者被分配在课余时间进行部分时间遮盖。在治疗结束 1 年后对患者进行长期观察，评估长期结果。
35 例患者中，4 例患者因拒绝进一步治疗而退出，1 例患者改为阿托品压抑治疗。30 例患者完成了部分时间遮盖治疗。90%（27/30）的患者依从性良好。弱视眼的平均 BCVA 显著提高（p<0.001），96.7%（29/30）的患者达到最终 BCVA 0.1 logMAR 或更好。长期结果中，87%的患者保持了 0.1 logMAR 或更好的 BCVA。4 名退出患者中，无一人在长期结果中达到 0.1 logMAR 或更好的 BCVA，即使连续佩戴眼镜也无法达到。
对 8 岁以上弱视儿童进行的部分时间遮盖治疗，在课余时间进行，治疗效果成功，在大多数情况下效果持久。
