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[巨大良性叶状肿瘤手术治疗的病例报告——是否需要切缘安全距?]

[Case reports of operative management of very large, benign phylloid tumors--is a safety margin necessary?].

作者信息

Abdallah A, Saklaoui O, Stückle C, Sommerer F, Hatzmann W, Audretsch W, Wesemann A, Zink M, Skoljarev L, Papadopoulos S

机构信息

Abteilung für Senologie, Frauenklinik, Marienhospital Herne, Herne, Germany.

出版信息

Gynakol Geburtshilfliche Rundsch. 2009;49(4):320-5. doi: 10.1159/000301107. Epub 2010 May 19.

Abstract

The phylloid tumor (PT, formerly called cystosarcoma phylloides) is a rare neoplasia of the female breast. Usually the PT is treated with breast-conserving surgery. In spite of progress in early diagnosis, PTs recur frequently--independently of tumor's degree of malignancy. Especially in cases of malignant PT, complete resection with tumor-free margins is seen as the only predictive marker for tumor recurrence or metastases. Benign PT is also often resected with wide tumor-free margins. Because of the tumor's occasionally enormous dimensions, this therapy concept makes breast-conserving surgery almost impossible. A simple enucleation of benign PT is an option to facilitate the preservation of breast tissue and a cosmetically satisfactory breast reconstruction. In the case of particularly large benign PT, enucleation even without wide margins prevents tumor recurrence.

摘要

叶状肿瘤(PT,以前称为叶状囊肉瘤)是女性乳腺的一种罕见肿瘤。通常,PT采用保乳手术治疗。尽管早期诊断取得了进展,但PT仍频繁复发——与肿瘤的恶性程度无关。特别是在恶性PT病例中,切缘无肿瘤的完整切除被视为肿瘤复发或转移的唯一预测指标。良性PT也常采用宽切缘无肿瘤切除。由于肿瘤偶尔尺寸巨大,这种治疗理念几乎使保乳手术无法进行。简单摘除良性PT是一种有助于保留乳腺组织并实现美容效果满意的乳房重建的选择。对于特别大的良性PT,即使切缘不宽的摘除也可防止肿瘤复发。

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