Devadoss Usha, Babu S, Cherian Vt
Department of Anaesthesia, Christian Medical College, Vellore - 632 004, Tamilnadu, India.
Indian J Anaesth. 2010 Jan;54(1):40-4. doi: 10.4103/0019-5049.60496.
Anaesthetic techniques may have a significant effect on intraoperative-evoked potentials (EP). The present study is designed to compare Propofol anaesthesia with Isoflurane (with or without nitrous oxide) during intraoperative somatosensory-evoked potential (SSEP) monitoring in 15 ASA Grade I and II patients undergoing surgery for intracranial tumours. SSEPs in response to median and posterior tibial nerve stimulation were recorded under four different anaesthetic conditions: 1) Propofol infusion and ventilation with air-oxygen, 2) Isoflurane, 1.0 MAC and ventilation with air-oxygen, 3) Isoflurane 1.0 MAC and ventilation with nitrous oxide-oxygen, and 4) Return to Isoflurane, 1.0 MAC and ventilation with air-oxygen. Intraoperative monitoring of somatosensory evoked potentials is best recordable using Propofol. The morphology of the EP is reproducible with Isoflurane. This effect is exaggerated when it is advisable to avoid nitrous oxide.
麻醉技术可能对术中诱发电位（EP）有显著影响。本研究旨在比较15例接受颅内肿瘤手术的美国麻醉医师协会（ASA）I级和II级患者在术中体感诱发电位（SSEP）监测期间丙泊酚麻醉与异氟烷（含或不含氧化亚氮）麻醉的效果。在四种不同麻醉条件下记录对正中神经和胫后神经刺激的SSEP：1）丙泊酚输注并采用空气-氧气通气；2）异氟烷，1.0 MAC并采用空气-氧气通气；3）异氟烷1.0 MAC并采用氧化亚氮-氧气通气；4）恢复至异氟烷，1.0 MAC并采用空气-氧气通气。术中体感诱发电位的监测使用丙泊酚时记录效果最佳。使用异氟烷时EP的形态可重复。当建议避免使用氧化亚氮时，这种影响会被放大。
