Tallarita T, Gurrieri C, Cappellani A, Corona D, Gagliano M, Giuffrida G, Caglià P, Fiamingo P, Giaquinta A, Sinagra N, Zerbo D, Virzì G, Veroux P, Veroux M
Vascular Surgery Unit, Department of Surgery, Transplantation and Advanced Technologies, University Hospital of Catania, Italy.
Transplant Proc. 2010 May;42(4):1171-3. doi: 10.1016/j.transproceed.2010.03.070.
Hemorrhoidal disease is a frequent cause of morbidity among the general population with a reported incidence of 4.4%, but little is known about its incidence and clinical features in kidney transplant recipients. Among 116 patients who had undergone kidney transplantation and were evaluated for hemorrhoidal disease, 82 had no hemorrhoids (70.6%), 28 (24%) had grade I hemorrhoids, and 6 (5.4%) had grade II hemorrhoids at the pretransplantation evaluation. Twenty-seven out of 116 recipients (22.4%) developed grade III or IV hemorrhoids after transplantation and underwent surgery. Hemorrhoidal disease was more frequent in patients with a pretransplantation history of hemorrhoids, with a rapid weight increase in the posttransplantation period, or who were aged between 30 and 50 years. Immunosuppressive therapy may play an important role in the worsening of hemorrhoidal disease among kidney transplant recipients. A prompt diagnosis and surgical treatment, whenever necessary, is mandatory for patients with clinical signs of worsening of hemorrhoids.
痔病是普通人群发病的常见原因，报告发病率为4.4%，但对于肾移植受者中痔病的发病率和临床特征知之甚少。在116例接受肾移植并接受痔病评估的患者中，82例无痔疮（70.6%），28例（24%）在移植前评估时有I度痔，6例（5.4%）有II度痔。116例受者中有27例（22.4%）在移植后出现III度或IV度痔并接受了手术。有移植前痔病史、移植后体重快速增加或年龄在30至50岁之间的患者中，痔病更为常见。免疫抑制治疗可能在肾移植受者痔病恶化中起重要作用。对于有痔疮恶化临床体征的患者，必要时应及时诊断并进行手术治疗。
