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儿童肠道移植:意大利首个成功案例系列。

Intestinal transplantation in children: the first successful Italian series.

作者信息

Colledan M, Stroppa P, Bravi M, Casotti V, Lucianetti A, Pinelli D, Zambelli M, Guizzetti M, Corno V, Aluffi A, Sonzogni V, Sonzogni A, D'Antiga L, Codazzi D

机构信息

Chirurgia III, Centro trapianto di fegato e di intestino Ospedali Riuniti di Bergamo, Italy.

出版信息

Transplant Proc. 2010 May;42(4):1251-2. doi: 10.1016/j.transproceed.2010.03.046.

DOI:10.1016/j.transproceed.2010.03.046
PMID:20534273
Abstract

The preliminary experience of the first Italian program of pediatric intestinal transplantation is presented herein. A multidisciplinary group with broad experience in pediatric solid organ transplantation started the program. Nine children with complications of chronic intestinal failure were listed for transplantation. One child died on the waiting list; one received an isolated liver transplantation; three isolated intestinal; three multivisceral; and one, a combined liver/intestine transplantation. There was no in-hospital mortality, and all children were weaned from parenteral nutrition. The recipient of the multivisceral graft died after 14 months for unknown causes. All other recipients are alive after a median follow-up of 13 months. Patient and graft actuarial survivals for recipients of intestinal grafts were 100% at 1 year and 75% at 2 years.

摘要

本文介绍了意大利首个小儿肠道移植项目的初步经验。一个在小儿实体器官移植方面经验丰富的多学科团队启动了该项目。九名患有慢性肠衰竭并发症的儿童被列入移植名单。一名儿童在等待名单上死亡;一名接受了单独的肝移植;三名接受了单独的肠道移植;三名接受了多脏器移植;一名接受了肝/肠联合移植。无住院死亡病例,所有儿童均停止了肠外营养。多脏器移植受者在14个月后因不明原因死亡。所有其他受者在中位随访13个月后均存活。肠道移植受者的患者和移植物精算生存率在1年时为100%,在2年时为75%。

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Intestinal transplantation in children: the first successful Italian series.儿童肠道移植:意大利首个成功案例系列。
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