帕金森病中与多巴胺激动剂相关的强迫性歌唱。
Compulsive singing associated with a dopamine agonist in Parkinson disease.
作者信息
Kataoka Hiroshi, Ueno Satoshi
机构信息
Department of Neurology, Nara Medical University, Kashihara, Nara, Japan.
出版信息
Cogn Behav Neurol. 2010 Jun;23(2):140-1. doi: 10.1097/WNN.0b013e3181c12af2.
OBJECTIVE
To describe a patient with Parkinson disease in whom compulsive singing developed without other types of pathologic behavior after starting treatment with pergolide.
MATERIAL
An 82-year-old woman with Parkinson disease was given pergolide (250 microg/d), without modifying the doses of other medications.
RESULTS
She started to hum the same melody and often sang songs repeatedly. Pergolide was discontinued, and the episodes of repetitive humming and singing were markedly decreased.
CONCLUSIONS
Our observations suggest that a dopamine agonist may contribute to compulsive singing in Parkinson disease.
目的
描述一名帕金森病患者，该患者在开始使用培高利特治疗后出现强迫性唱歌，且无其他类型的病理行为。
材料
一名82岁的帕金森病女性患者，在未改变其他药物剂量的情况下，给予培高利特（250微克/天）。
结果
她开始哼唱同一旋律，且经常反复唱歌。停用培高利特后，重复性哼唱和唱歌的发作明显减少。
结论
我们的观察结果表明，多巴胺激动剂可能导致帕金森病患者出现强迫性唱歌。
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