Nanba K, Iwata K
Department of Ophthalmology, Niigata University School of Medicine, Japan.
Nippon Ganka Gakkai Zasshi. 1991 Feb;95(2):174-83.
Optic disc measurements were performed with computerized image analysis (Rodenstock Optic Nerve Head Analyzer) in one eye of each patient of 74 normal controls, 41 ocular hypertensives and 41 patients with early stage glaucoma. In normal controls, the rim area was 1.62 +/- 0.48 mm2 (mean +/- s.d.), cup area 0.80 +/- 0.41mm2, cup volume 0.34 +/- 0.16mm3, cup/disc ratio 0.43 +/- 0.19. For Ocular hypertensives, rim area was 1.32 +/- 0.44mm2, cup area 1.32 +/- 0.78mm2, cup volume 0.56 +/- 0.41mm2, cup/disc ratio 0.51 +/- 0.41. For glaucomas, the rim area was 1.07 +/- 0.47mm2, cup area 1.3 +/- 0.78mm2, cup volume 0.75 +/- 0.40mm3, cup/disc ratio 0.65 +/- 0.19. Statistically significant differences were found among the three groups for these parameters. In spite of the wide distribution and overlap of the values of optic disc parameters among the three groups, normal subjects with an optic disc area of greater than or equal to 3.0mm2 showed clear differences in optic disc parameters compared to ocular hypertensive and glaucoma cases. From these results, cases with larger discs seem to be more vulnerable to raised IOPs.
对74名正常对照者、41名高眼压症患者和41名早期青光眼患者的单眼进行视盘测量，采用计算机图像分析（罗丹斯托克视神经乳头分析仪）。在正常对照者中，视盘边缘面积为1.62±0.48mm²（均值±标准差），杯盘面积为0.80±0.41mm²，杯盘容积为0.34±0.16mm³，杯盘比为0.43±0.19。高眼压症患者的视盘边缘面积为1.32±0.44mm²，杯盘面积为1.32±0.78mm²，杯盘容积为0.56±0.41mm²，杯盘比为0.51±0.41。青光眼患者的视盘边缘面积为1.07±0.47mm²，杯盘面积为1.3±0.78mm²，杯盘容积为0.75±0.40mm³，杯盘比为0.65±0.19。这三组在这些参数上存在统计学显著差异。尽管三组视盘参数值分布广泛且有重叠，但视盘面积大于或等于3.0mm²的正常受试者与高眼压症和青光眼患者相比，视盘参数存在明显差异。从这些结果来看，视盘较大的病例似乎更容易受到眼压升高的影响。
