Kaszap B, Daecke W
Klinikum der Johann Wolfgang Goethe-Universität Frankfurt am Main, Orthopädische Universitätsklinik Friedrichsheim, Frankfurt am Main.
Handchir Mikrochir Plast Chir. 2010 Jun;42(3):177-86. doi: 10.1055/s-0030-1254122. Epub 2010 Jun 9.
Only a few diseases are treated by such a wide spectrum of therapeutic options as avascular necrosis of the lunate bone. The ultimate aim of all these very different biomechanical concepts is to avoid carpal collapse and wrist osteoarthritis. To be able to assess the efficiency of the separate operative methods, a crucial analysis of the present long-term publications is needed. We have reviewed 20 long-term studies (mean follow-up interval >10 years) to evaluate the different therapeutic options. The main results of these publications have been collected here. Decompression osteotomies can provide in the long term a ROM of 80-87%, a pain-free state in 20-67%, a progression in 20-50% and osteoarthritis in 25-73% of the cases. In contrast, revascularisation procedures can provide in the long term a ROM of 68-81%, pain-free state in 35-72%, progression in 11-100% and osteoarthritis in 32-100%. Salvage procedures can be applied at a later stage of the disease; they can provide in the long term a ROM of 61-78%, pain-free state in 38-50%, and osteoarthritis in 24-48% of the cases. Based on the listed long-term studies, it was demonstrated that a differentiated therapy should be based on the anatomic conditions and stage of the disease. Due to the restricted comparability of the studies, the formulation of a common therapy algorithm was not possible.
只有少数几种疾病能像月骨缺血性坏死那样有如此广泛的治疗选择。所有这些截然不同的生物力学概念的最终目标都是避免腕骨塌陷和腕关节骨关节炎。为了能够评估各种手术方法的效果,需要对目前的长期出版物进行关键分析。我们回顾了20项长期研究(平均随访间隔>10年),以评估不同的治疗选择。这些出版物的主要结果在此汇总。减压截骨术长期来看,在80 - 87%的病例中可提供活动范围,20 - 67%的病例无痛,20 - 50%的病例病情进展,25 - 73%的病例出现骨关节炎。相比之下,血管重建手术长期来看,在68 - 81%的病例中可提供活动范围,35 - 72%的病例无痛,11 - 100%的病例病情进展,32 - 100%的病例出现骨关节炎。挽救手术可在疾病后期应用;长期来看,在61 - 78%的病例中可提供活动范围,38 - 50%的病例无痛,24 - 48%的病例出现骨关节炎。基于所列的长期研究表明,个体化治疗应基于解剖条件和疾病阶段。由于研究的可比性有限,无法制定通用的治疗方案。