Centre for Synthesis and Chemical Biology, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
Bioconjug Chem. 2010 Jul 21;21(7):1130-3. doi: 10.1021/bc100051p.
The synthesis and properties of a new visible red/near-infrared fluorochrome for bioconjugation via activated ester groups is described. Representative amine conjugations with amino acid lysine and proteins lysozyme and trypsin were successfully accomplished.
描述了一种新的可见红色/近红外荧光染料的合成及其性质,该染料可通过活化酯基团进行生物偶联。成功地完成了与氨基酸赖氨酸以及蛋白质溶菌酶和胰蛋白酶的代表性胺偶联。