检测母亲及其子女唾液样本中具有胶原结合特性的口腔链球菌。
Detection of oral streptococci with collagen-binding properties in saliva specimens from mothers and their children.
机构信息
Department of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Osaka, Japan.
出版信息
Int J Paediatr Dent. 2010 Jul;20(4):254-60. doi: 10.1111/j.1365-263X.2010.01047.x.
BACKGROUND
Approximately 10-20% of Streptococcus mutans strains have been reported to possess collagen-binding properties, whereas other species in the oral cavity with those properties remain to be elucidated. Aim. To identify strains with collagen-binding properties and analyse their characteristics in comparison with S. mutans.
DESIGN
A total of 110 expectorated saliva specimens were collected from 55 pairs of mothers and their children. Bacterial strains with collagen-binding properties were isolated and the species specified. In addition, strains with collagen-binding properties isolated from mother-child pairs were analysed using molecular biological approaches.
RESULTS
The detection frequency of strains with collagen-binding properties was shown to be 40.9%, among which S. salivarius was the most frequently detected, followed by S. mutans. The collagen-binding activity of the S. mutans group was the highest, followed by S. salivarius. In addition, S. mutans and S. salivarius strains from 3 and 1 mother-child pairs, respectively, were shown to be the same clones.
CONCLUSIONS
Our results indicate that S. mutans and S. salivarius are major species with collagen-binding properties in the oral cavity, and that strains with such properties may be related to mother-child transmission.
背景
约有 10-20%的变形链球菌菌株被报道具有胶原结合特性，而口腔中具有这些特性的其他物种仍有待阐明。目的。鉴定具有胶原结合特性的菌株，并分析其与变形链球菌的特性比较。
设计
从 55 对母子中收集了 110 份唾液标本。分离具有胶原结合特性的细菌菌株并指定其种类。此外，还使用分子生物学方法分析了从母子对中分离出的具有胶原结合特性的菌株。
结果
具有胶原结合特性的菌株的检测频率为 40.9%，其中唾液链球菌最常被检测到，其次是变形链球菌。变形链球菌组的胶原结合活性最高，其次是唾液链球菌。此外，分别来自 3 对母子和 1 对母子的变形链球菌和唾液链球菌菌株被证明是相同的克隆。
结论
我们的结果表明，变形链球菌和唾液链球菌是口腔中具有胶原结合特性的主要菌种，具有这种特性的菌株可能与母婴传播有关。
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