School of History and Philosophy, University of New South Wales, Sydney, New South Wales, Australia.
Int J Rheum Dis. 2010 May;13(2):125-31. doi: 10.1111/j.1756-185X.2010.01461.x.
The historical significance of the Medici family of Florence is widely recognised, but the diseases which afflicted leading members of this family have only been scientifically studied in recent decades. Paleopathological findings on exhumed skeletons, supplemented by medical descriptions in historical documents, have permitted a retrospective diagnosis of a triple pathological syndrome in the senior branch of the Medici family. Peripheral joint and spinal conditions, with the presence of skin disease, are identified in several generations of the family in the 15th century and are presented as the 'Medici syndrome'. Radiological findings are compared with macro- and microscopical descriptions in the diagnosis of the peripheral joint disease and spinal ankylosis/stenosis within the syndrome.
佛罗伦萨的美第奇家族的历史意义得到了广泛认可，但直到最近几十年，人们才对该家族主要成员所患的疾病进行了科学研究。对挖掘出的骨骼进行古病理学研究，并结合历史文献中的医学描述，使得人们能够回溯性地诊断出美第奇家族中一个高级分支所患的三重病理综合征。15 世纪，该家族的几代人都出现了外周关节和脊柱疾病，同时伴有皮肤病，这种情况被确定为“美第奇综合征”。在该综合征中，通过放射学发现与对外周关节疾病和脊柱强直/狭窄的宏观和微观描述进行比较，从而做出诊断。
