School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA.
Appl Spectrosc. 2010 Jun;64(6):601-6. doi: 10.1366/000370210791414326.
The application of surface-enhanced Raman spectroscopy (SERS) to characterizing bacteria is an active area of investigation. Micro- and nano-structured SERS substrates have enabled detection of pathogens present in biofluids. Several publications have focused on determining the spectral bands characteristic of bacteria from different species and cell lines. In this report, the spectra of fifteen commonly used bacterial growth media are presented. In many instances, these spectra are similar to published spectra purportedly characteristic of specific bacterial species. The findings presented herein suggest that bacterial fingerprinting by SERS requires further examination.
表面增强拉曼光谱（SERS）在细菌特征分析中的应用是一个活跃的研究领域。微纳结构的 SERS 基底已经可以实现对生物流体中病原体的检测。有几项出版物都集中于确定来自不同物种和细胞系的细菌的特征光谱带。在本报告中，展示了十五种常用细菌生长培养基的光谱。在许多情况下，这些光谱与据称是特定细菌物种特征的已发表光谱相似。本文提出的研究结果表明，SERS 的细菌指纹分析需要进一步研究。
