Center for Evaluation Research and Surveys, National Institute of Public Health, Cuernavaca, Morelos, Mexico.
Curr Opin HIV AIDS. 2010 May;5(3):232-6. doi: 10.1097/COH.0b013e32833860d3.
Increasing demand for HIV treatment and limited resource availability will require the optimization of treatment programming to not only improve individual treatment outcomes, but also to maximize overall benefit for available resources.
Available research, although recognizing the importance of ensuring or improving treatment adherence, largely focuses on patient barriers or incentives. More research is necessary to examine how decisions made at all levels of treatment programming affect treatment outcomes.
Explicit decisions regarding treatment access, initiation, drug combinations, and potential termination of treatment along with addressing incentives and barriers to treatment adherence are necessary to maximize the overall benefit for available resources. This factor will depend on the involvement of the three main treatment actors, program managers, health practitioners, and patients.
HIV 治疗需求的不断增加和有限资源的可获得性将要求优化治疗方案规划，不仅要改善个体的治疗结果，还要使现有资源的整体效益最大化。
现有的研究虽然认识到确保或改善治疗依从性的重要性，但主要集中在患者的障碍或激励因素上。需要更多的研究来研究治疗方案规划的各个层面的决策如何影响治疗结果。
明确关于治疗机会、启动、药物组合以及潜在治疗终止的决策，以及解决治疗依从性的激励和障碍，对于使现有资源的整体效益最大化是必要的。这一因素将取决于三个主要治疗参与者——项目管理人员、卫生从业人员和患者——的参与。
