Siminialayi I M, Emem-Chioma P C, Odia O J
Department of Pharmacology, College of Health Sciences, University of Port Harcourt, Choba, Rivers State, Nigeria.
Niger Postgrad Med J. 2010 Jun;17(2):147-53.
It was not clear for a while, which of the definitions of metabolic syndrome best predicted those at risk of cardiovascular disease and diabetes but recent studies have confirmed the predictive ability of various definitions of metabolic syndrome and have reported that the International Diabetes Federation definition, although more sensitive is associated with a higher false positive predictive rate.
To determine the prevalence of metabolic syndrome, using the International Diabetes Federation and Adult Treatment Panel III definitions among adult Nigerians attending Family Medicine Clinics at two hospitals in Rivers State Nigeria.
Adult subjects attending family medicine clinics at an urban and a sub-urban hospital in Rivers State, Nigeria were bled after an overnight fast, and venous blood obtained for lipid studies and fasting plasma glucose estimations. Measurements were made to determine height, weight, waist circumference and blood pressure. The data obtained was analysed using SPSS for Windows software version 12 and Epi info version 6.04D RESULTS: The prevalence of metabolic syndrome was 19.81% (ATP III) and 23.19% (IDF) at one centre and 34.17% (ATP III) and 35.42% (IDF) at the other centre.
The prevalence of metabolic syndrome by the two definitions was significantly higher at the second centre. The difference in the prevalence rates by the two definitions was also much smaller in the second centre perhaps because the second centre had more women and the mean age of the subjects was significantly higher.
有一段时间尚不清楚哪种代谢综合征的定义能最好地预测心血管疾病和糖尿病的风险，但最近的研究证实了代谢综合征各种定义的预测能力，并报告称国际糖尿病联盟的定义虽然更敏感，但假阳性预测率较高。
在尼日利亚河流州两家医院的家庭医学诊所就诊的成年尼日利亚人中，使用国际糖尿病联盟和成人治疗小组第三次报告的定义来确定代谢综合征的患病率。
在尼日利亚河流州一家城市医院和一家郊区医院的家庭医学诊所就诊的成年受试者在禁食过夜后采血，采集静脉血进行血脂研究和空腹血糖测定。测量身高、体重、腰围和血压。使用SPSS for Windows软件版本12和Epi info版本6.04D对获得的数据进行分析。结果：在一个中心，代谢综合征的患病率为19.81%（成人治疗小组第三次报告的定义）和23.19%（国际糖尿病联盟的定义），在另一个中心为34.17%（成人治疗小组第三次报告的定义）和35.42%（国际糖尿病联盟的定义）。
两种定义下代谢综合征的患病率在第二个中心显著更高。两种定义下患病率的差异在第二个中心也小得多，可能是因为第二个中心女性更多，且受试者的平均年龄显著更高。
