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曲霉感染罕见地表现为脓胸。

A rare presentation of aspergillus infection as empyema thoracis.

作者信息

Goel Manoj K, Juneja Deven, Jain Satinder K, Chaudhuri Saikiran, Kumar Ajay

机构信息

Department of Pulmonology, Critical Care and Sleep Medicine, Delhi Heart and Lung Institute 3 MM - II Panchkuian Road, New Delhi - 110 055, India.

出版信息

Lung India. 2010 Jan;27(1):27-9. doi: 10.4103/0970-2113.59265.

DOI:10.4103/0970-2113.59265
PMID:20539768
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2878709/
Abstract

A 57-year-old diabetic and hypertensive man presented with a short history of fever, dry cough and right side chest pain. A chest radiograph showed right pleural based homogenous shadow in middle and lower zones with obliteration of right costo-phrenic angle suggestive of right side effusion. Aspiration of pleural fluid revealed frank pus for which inter-costal tube drainage was performed. Due to persistence of empyema, the patient was subjected to thoracoscopy. Thoracoscopy showed multiloculated empyema. Thoracoscopic pleural biopsy and fluid showed septate fungal hyphae. Thoracotomy and parietal pleurectomy, with resection of part of right lower lobe, was carried out. Pleural fluid, pleural and lung tissue culture grew Aspergillus fumigatus. The patient showed good recovery with voriconazole after thoracotomy.

摘要

一名57岁的糖尿病和高血压男性患者,出现发热、干咳和右侧胸痛的病史较短。胸部X线片显示右中下肺野有均匀阴影,右肋膈角消失,提示右侧胸腔积液。胸腔穿刺抽出脓性液体,遂行肋间置管引流。由于脓胸持续存在,患者接受了胸腔镜检查。胸腔镜检查显示为多房性脓胸。胸腔镜胸膜活检及胸水检查发现有分隔的真菌菌丝。遂行开胸手术及壁层胸膜切除术,并切除右下叶部分肺组织。胸水、胸膜及肺组织培养均生长出烟曲霉。开胸手术后患者使用伏立康唑治疗,恢复良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd9/2878709/72dda881dc99/LI-27-27-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd9/2878709/0b93eb08a0b7/LI-27-27-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd9/2878709/2722de87d894/LI-27-27-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd9/2878709/72dda881dc99/LI-27-27-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd9/2878709/0b93eb08a0b7/LI-27-27-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd9/2878709/2722de87d894/LI-27-27-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fd9/2878709/72dda881dc99/LI-27-27-g003.jpg

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本文引用的文献

1
Aspergillus fumigatus empyema, arthritis, and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole.一名肺移植患者发生烟曲霉菌性脓胸、关节炎和跟骨骨髓炎,使用泊沙康唑成功治疗。
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Voriconazole: a new triazole antifungal agent.伏立康唑:一种新型三唑类抗真菌药物。
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Unusual sojourn of not-so-unusual pathogens.不那么常见的病原体的异常寄居情况。
Lung India. 2014 Apr;31(2):107-9. doi: 10.4103/0970-2113.129811.
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Aspergillosis and other systemic mycoses. The growing problem.曲霉病及其他系统性真菌病。日益严重的问题。
JAMA. 1979 Oct 12;242(15):1631-5.